transdermal ozone reduces vaginal IgG levels by ~45%, signaling lower chronic immune activation

Ozone therapy decreased vaginal IgG levels by 45% (p<0.05), indicating reduction in chronic inflammatory immune activation.

What this means for you

When your immune system stays in a low-grade 'on' state for too long, it can quietly drain energy and disrupt tissue health. A measurable drop in IgG — an antibody tied to ongoing immune activity — suggests the body's local defenses are rebalancing rather than staying stuck in a reactive loop. That kind of immune recalibration is linked to less discomfort, better tissue resilience, and a calmer inflammatory baseline.

The published research

The New Method of Treatment of Inflammatory Diseases of
· 2000
This page describes a documented finding about the underlying wellness technology. It is not a marketing claim about any specific device. For information about HOCATT specifically, visit hocatt.com.