transdermal ozone triggers a net antioxidant protective state by upregulating the body's own defense enzymes
Ozone therapy by brief oxidative stress stimulation upregulates the endogenous antioxidant defense system (SOD, CAT, GSH-Px, GSH) to levels that surpass the increase in lipid peroxidation (TBARS), resulting in a net antioxidant protective state.
What this means for you
Your body has built-in antioxidant enzymes — SOD, catalase, glutathione — that neutralize the oxidative stress linked to aging, inflammation, and low energy. A brief, controlled oxidative signal from ozone appears to activate these defenses beyond the stress itself, leaving your system in a stronger protective state overall. Think of it like a workout for your cellular cleanup crew.
The published research
Mediators of Inflammation • 2005:4 (2005) 221–227 • PII: S0962935105506057 • DOI: 10.1155/MI.2005.221
· 2005
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