transdermal ozone exposure triggers a brief, self-resolving oxidative stress response

Quasi-total-body transdermal O2-O3 exposure for 20 minutes caused a statistically significant increase in plasma TBARS (lipid peroxidation products) that returned to baseline within 24 hours, indicating transient and reversible oxidative stress.

What this means for you

A short-lived rise in oxidative markers — one that fully resets within 24 hours — is thought to act like a mild hormetic signal, nudging the body's own antioxidant defenses into action. This kind of transient, controlled stress is similar to what happens during exercise: a temporary challenge that the body adapts to and recovers from naturally.

The published research

Eur J Appl Physiol (1999) 80: 549±554 Ó Springer-Verlag 1999
· 1999
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