transdermal ozone boosts superoxide dismutase (SOD) activity by over 6× in compromised tissue

Ozone therapy significantly activated superoxide dismutase (SOD) activity (from 1.09 ± 0.13 to 6.87 ± 0.32 U/ml/min, P<0.05) in diabetic patients, far exceeding both antibiotic-treated and healthy reference values.

What this means for you

SOD is one of your body's most powerful internal antioxidants — it neutralizes the free radicals that drive inflammation, accelerate aging, and slow recovery. When SOD activity rises this significantly, your cells are better equipped to handle oxidative stress, which most people experience as less fatigue, faster bounce-back, and a general sense of resilience.

The published research

European Journal of Pharmacology 523 (2005) 151 – 161
· 2005
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