transdermal ozone exposure measurably reduces plasma protein thiol groups, signaling protein oxidation

Transdermal O2-O3 exposure caused a significant decrease in plasma protein thiol groups (PTG), indicating protein oxidation, an effect not seen with O2 alone.

What this means for you

Protein thiol groups are markers researchers track to understand how the body responds to oxidative stress. When ozone is absorbed through the skin, it triggers a measurable oxidative response in the bloodstream — something oxygen alone doesn't produce. This is the kind of biological signal scientists study when exploring how the body adapts to controlled oxidative challenges.

The published research

Eur J Appl Physiol (1999) 80: 549±554 Ó Springer-Verlag 1999
· 1999
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