transdermal ozone normalizes oxidative stress markers to healthy baseline levels

Ozone treatment normalized total hydroperoxide levels in diabetic foot patients (from 145.4 ± 31.6 μM to 106.3 ± 30.9 μM, not significantly different from healthy controls at 103.8 ± 17.7 μM), while antibiotic therapy produced no change.

What this means for you

Hydroperoxides are a key marker of oxidative stress — the cellular wear-and-tear linked to inflammation, slow recovery, and accelerated aging. When ozone exposure brought these levels back to a healthy range (while antibiotics made no difference), it suggests ozone may support the body's ability to rebalance its oxidative load in a meaningful way.

The published research

European Journal of Pharmacology 523 (2005) 151 – 161
· 2005
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