Transdermal ozone introduces controlled, low-dose oxidative signaling through the skin, which peer-reviewed research links to upregulated immune activity and enhanced white blood cell signaling pathwa
Stimulation of immune system and white blood cell production
What this means for you
Strengthens immune defense against pathogens and disease
The published research
Ozone therapy: An overview of pharmacodynamics, current research, and clinical utility
Medical Gas Research · 2017
The review explicitly documents ozone's immune-stimulating effects, including a dedicated 'Immune system activation' section noting increases in interferon, TNF, IL-2, and IL-8, activation of NF-κB, and increased secretions of macrophages and leukocytes. It also reports Hsp70 induction that 'stimulates several immune system responses in lymphocytes and macrophages,' directly supporting the documen
This page describes a documented finding about the underlying wellness technology. It is not a marketing claim about any specific device. For information about HOCATT specifically, visit hocatt.com.