transdermal ozone sharply reduces glycated protein markers in damaged tissue
Ozone therapy significantly reduced fructolysine (Amadori product / glycated protein precursor) levels in diabetic foot patients from 1354 ± 110 to 250 ± 27 relative units after 20 days, a significantly greater reduction than antibiotic therapy (789 ± 60, P<0.01).
What this means for you
Glycated proteins are a byproduct of excess sugar binding to tissue — they accumulate with age and metabolic stress and are linked to slower recovery and cellular aging. When these markers drop significantly, it suggests the tissue environment is shifting toward a healthier, less damaged state — which most people notice as better skin quality, faster wound closure, and improved resilience over time.
The published research
This page describes a documented finding about the underlying wellness technology. It is not a marketing claim about any specific device. For information about HOCATT specifically, visit hocatt.com.