microcurrent-induced shear stress prompts blood vessels to release natural signaling molecules that support dilation
Shear stress on vascular endothelial cells triggers release of soluble ecto-enzymes ATPase and 5'-nucleotidase along with endogenous ATP, initiating a cascade of purinergic vasodilatory signaling.
What this means for you
When blood vessels sense physical stress, they release their own chemical messengers — including ATP — that tell surrounding tissue to open up and let more blood through. Better vessel responsiveness means more oxygen and nutrients reaching your muscles, skin, and organs, which most people feel as improved circulation, warmth, and faster recovery.
The published research
Augmentation of Muscle Blood Flow by Ultrasound Cavitation Is Mediated by ATP and Purinergic Signaling
Circulation · 2017
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