PEMF raises IGF-1 and lowers myostatin, supporting muscle protein synthesis

PEMF treatment significantly upregulated serum IGF-1 levels while concurrently decreasing serum myostatin (MSTN) in osteosarcopenic rats, promoting anabolic muscle protein synthesis.

What this means for you

IGF-1 is a key signal your body uses to build and maintain muscle, while myostatin is the brake that slows that process down. When IGF-1 goes up and myostatin goes down together, the conditions for preserving lean muscle mass improve — something most people notice as better strength, easier recovery, and less of the gradual muscle loss that comes with aging.

The published research

Pulsed electromagnetic field effectively improves musculoskeletal degeneration and inflammation levels in a rat model of osteosarcopenia: an experimental study
Frontiers in Immunology · 2026
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