PEMF triggers a 2.5–2.9x rise in anti-inflammatory enzyme signaling in skin and immune cells

PEMF treatment was followed by a 2.5- to 2.9-fold increase in heme oxygenase 1 mRNA in human dermal fibroblasts, epidermal keratinocytes, and mononuclear cells, peaking 1.5 hours after treatment, suggesting promotion of heme catabolism and anti-inflammatory signaling.

What this means for you

Heme oxygenase-1 is one of your body's key built-in responses to cellular stress — it helps break down inflammatory byproducts and calm overactive immune signaling. A meaningful rise in this enzyme activity, peaking about 90 minutes after a session, suggests your skin and immune cells are actively shifting toward a recovery and repair state.

The published research

Effect of pulsed electromagnetic field treatment on programmed resolution of inflammation pathway markers in human cells in culture
Journal of Inflammation Research · 2015
This page describes a documented finding about the underlying wellness technology. It is not a marketing claim about any specific device. For information about HOCATT specifically, visit hocatt.com.