ozonized lipids produce a broad dicarboxylic acid profile in urine, signaling active metabolic processing

Oral administration of ozonized trilinolein to Wistar rats produced a broad urinary dicarboxylic acid profile including nonanedioic acid at 79 ± 4 µg/mg creatinine, heptanedioic acid at 23.4 ± 0.9 µg/mg creatinine, and multiple unsaturated dicarboxylic acids, mirroring the profile seen with ozonized sunflower oil.

What this means for you

When ozonized fats are metabolized, the body breaks them down into measurable byproducts — a sign that ozone-modified compounds are being actively processed rather than ignored. This kind of metabolic engagement is what researchers look for when studying how ozone-based compounds interact with the body's natural chemistry.

The published research

Ozonized Unsaturated Triglycerides as Precursors of
· 1990
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