transdermal ozone triggers upregulation of four key antioxidant enzymes

Ozone therapy upregulates antioxidant enzymes including superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), glutathione reductase (GSH-Rd), and catalase (CAT) in response to the acute oxidative stress it induces.

What this means for you

These enzymes — SOD, catalase, and two forms of glutathione — are your body's built-in defense against oxidative damage. When they're more active, your cells are better equipped to handle the daily wear from stress, inflammation, and aging. Most people associate stronger antioxidant activity with faster recovery, more resilience, and a general sense of feeling less run-down.

The published research

Archives of Medical Research 37 (2006) 425–435
· 2006
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