transdermal ozone exposure modulates TNF-α expression in splenic immune tissue
O3/O2 pneumoperitoneum significantly enhanced the urethane-induced reduction in splenic TNFα mRNA expression (P<0.05), demonstrating drug-specific immunomodulatory interactions.
What this means for you
TNF-α is a key signaling molecule your immune system uses to manage inflammation. When its activity is modulated rather than simply suppressed or amplified, the body may be better equipped to calibrate its inflammatory response — which matters for recovery, immune resilience, and how you feel day to day.
The published research
In uence of O3/O2–pneumoperitoneum
· 1987
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