ozone preconditioning lowers TNF-α and rebalances the body's oxidant-antioxidant ratio

Ozone oxidative preconditioning reduces TNF-α release and modulates antioxidant-prooxidant intracellular balance in mice during endotoxic shock, indicating ozone has anti-inflammatory cytokine-modulating properties.

What this means for you

TNF-α is a key driver of inflammation — when it runs high, you feel it as fatigue, soreness, and slow recovery. Research suggests ozone exposure can dial that signal down while simultaneously boosting your body's own antioxidant defenses, a combination that supports a calmer, more resilient internal environment.

The published research

Mediators of Inflammation • 2005:4 (2005) 221–227 • PII: S0962935105506057 • DOI: 10.1155/MI.2005.221
· 2005
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