transdermal ozone increases TGF-β expression in skin cells, supporting collagen production
Topical ozone upregulated TGF-β expression in dermal fibroblasts, epidermal cells, and keratinocytes of hair follicles at the wound site on day 7, correlating with increased collagen synthesis.
What this means for you
TGF-β is a signaling protein your skin uses to rebuild itself — it tells fibroblasts to produce collagen, the structural protein that keeps skin firm and resilient. When this signal is more active, your skin's natural repair process gets a meaningful nudge, which matters for recovery, texture, and how well your skin holds up over time.
The published research
Therapeutic effects of topical application of ozone on acute cutaneous wound healing.
Journal of Korean medical science · 2009
This page describes a documented finding about the underlying wellness technology. It is not a marketing claim about any specific device. For information about HOCATT specifically, visit hocatt.com.