transdermal ozone acts as a superoxide scavenger, targeting oxidative stress pathways linked to metabolic dysfunction

Ozone's pharmacodynamic effect in diabetic foot treatment can be ascribed to its role as a superoxide scavenger, targeting the common link between the four metabolic routes (polyol pathway, advanced glycation end-products, protein kinase C activation, hexosamine pathway) associated with diabetic pathology.

What this means for you

Superoxide buildup is a key driver of the cellular damage that accumulates when blood sugar regulation is disrupted. By neutralizing superoxide, ozone may help interrupt the chain reaction across multiple metabolic pathways that contributes to oxidative stress, inflammation, and tissue breakdown — things that matter deeply for long-term metabolic wellness and recovery.

The published research

European Journal of Pharmacology 523 (2005) 151 – 161
· 2005
This page describes a documented finding about the underlying wellness technology. It is not a marketing claim about any specific device. For information about HOCATT specifically, visit hocatt.com.