ozone exposure depletes vitamins C and E and raises oxidative markers in the outer skin layers

Ozone exposure of mouse skin causes depletion of vitamins C and E and increased epidermal malondialdehyde (MDA) production, primarily in the external layers of the epidermis.

What this means for you

Your skin's outermost layers use vitamins C and E as a frontline defense against oxidative stress. Understanding how ozone interacts with these antioxidants helps explain why replenishing them — through nutrition or topical support — matters for skin resilience, tone, and how well your complexion holds up over time.

The published research

Eur J Appl Physiol (1999) 80: 549±554 Ó Springer-Verlag 1999
· 1999
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