transdermal ozone restores red blood cell catalase activity to near-normal levels in arthritic tissue

Therapeutic ozone administration significantly restored erythrocyte catalase (CAT) activity in arthritic rats (128.7 ± 8.8 µmoles H₂O₂/min/gHb) to normal levels (124.5 ± 16.7), compared to untreated arthritic rats (100.8 ± 8.1).

What this means for you

Catalase is one of your body's frontline enzymes for breaking down harmful hydrogen peroxide before it damages cells. When inflammation is high, this defense system gets depleted. Ozone exposure appears to help restore that enzymatic activity — which may support your body's ability to manage oxidative stress during periods of joint inflammation or physical strain.

The published research

EFFECT OF OZONE OXIDATIVE PRECONDITIONING ON OXIDANT STATUS OF
· 1999
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