ozone preconditioning normalizes excess antioxidant enzyme activity in liver tissue under stress
Ozone oxidative preconditioning normalized catalase (CAT) activity in hepatic tissue during ischaemia–reperfusion (282 ± 27 U/g protein) compared to the markedly elevated levels in untreated I/R animals (764 ± 53 U/g protein), suggesting prevention of excessive oxidative stress.
What this means for you
When the body is under serious oxidative stress, antioxidant enzymes can swing wildly out of balance — a sign the system is overwhelmed. This finding suggests ozone preconditioning may help keep that response more measured and controlled, which is associated with less cellular damage and a more resilient recovery from physical stress.
The published research
Liver International 2004, 24, 55–62 Copyright r Blackwell Munksgaard 2004
· 2004
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