transdermal ozone shifts oxygen release from red blood cells to oxygen-starved tissues
Ozone therapy increases ATP and 2,3-diphosphoglycerate (2,3-DPG) in red blood cells by enhancing phosphofructokinase activity and glycolytic rate, leading via the Bohr effect to a rightward shift in the oxyhemoglobin dissociation curve and improved oxygen unloading to ischemic tissues.
What this means for you
When red blood cells release oxygen more readily, tissues that are struggling to get enough — muscles, skin, organs — get better supplied. Most people notice this as improved energy, faster recovery after exertion, and a general sense that their body is working more efficiently.
The published research
Ozone therapy: An overview of pharmacodynamics, current research, and clinical utility
Medical Gas Research · 2017
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