low-dose ozone activates nitric oxide pathways linked to liver protection
Ozone administration under controlled conditions (15 days, low doses by rectal insufflation) may prime and activate genes associated with NOS expression, promoting nitric oxide formation at concentrations required for protecting against liver ischaemia–reperfusion injury.
What this means for you
Nitric oxide is one of your body's key signaling molecules — it helps regulate blood flow, reduce inflammation, and protect tissues under stress. When ozone activates the genes that produce it, your body may be better equipped to handle the kind of oxidative and circulatory stress that quietly accumulates over time.
The published research
Liver International 2004, 24, 55–62 Copyright r Blackwell Munksgaard 2004
· 2004
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