transdermal ozone activates a key cellular signaling pathway that regulates immune protein production

Ozone-induced H₂O₂ activates NF-κB, which switches on the synthesis of cytokines, with this pathway modulated by intracellular antioxidants including reduced glutathione, ascorbic acid, GSH peroxidase, and catalase.

What this means for you

Your immune system relies on precise chemical signals to coordinate its response to stress, inflammation, and recovery. When this signaling pathway is activated — and kept in balance by your body's own antioxidants like glutathione and vitamin C — it supports a more responsive, well-regulated immune system. That kind of balance is linked to better resilience, faster recovery, and lower chronic inflammation over time.

The published research

OZONE AS A MODULATOR OF THE IMMUNE SYSTEM
· 1990
This page describes a documented finding about the underlying wellness technology. It is not a marketing claim about any specific device. For information about HOCATT specifically, visit hocatt.com.