transdermal ozone activates NF-κB signaling, prompting immune-related protein production
Ozone acts as a mild enhancer of the immune system through activation of the gene regulatory nuclear factor kappa B (NF-κB) by H₂O₂, switching on genes responsible for synthesis of acute phase reactants and interleukins.
What this means for you
NF-κB is a key switch your body uses to coordinate immune responses. When ozone gently activates this pathway, it nudges your system to produce proteins that support immune readiness — which may help your body stay resilient during periods of stress, recovery, or seasonal challenges.
The published research
EFFECT OF OZONE OXIDATIVE PRECONDITIONING ON OXIDANT STATUS OF
· 1999
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