transdermal ozone activates neutrophil immune response via plasma mediators within 24 hours
The stimulating effect of ozone on neutrophil chemiluminescence was not observed immediately after ozone administration but became evident 24 hours later, suggesting the mechanism involves accumulation of plasma-borne mediators rather than direct cellular activation.
What this means for you
Neutrophils are your immune system's first responders. When their oxygen-dependent activity ramps up — even gradually over 24 hours — it reflects your body building a more coordinated inflammatory response. This kind of delayed, sustained activation may support recovery and resilience more effectively than an immediate spike.
The published research
The Mechanism of the Anti-Inflammatory Effect of
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