ozone upregulates miR-21-5p in fibroblasts, activating cell migration signals
Ozone therapy upregulates miR-21-5p expression in fibroblasts, which knockdowns RASA1 (a RasGAP protein), thereby activating Ras signalling and enhancing fibroblast migration and wound healing.
What this means for you
Fibroblasts are the cells your skin relies on to close wounds and rebuild tissue. When their migration signals are activated, the repair process moves faster and more efficiently — which most people notice as quicker recovery from cuts, abrasions, or skin stress.
The published research
Ozone therapy for skin diseases: Cellular and molecular mechanisms.
International wound journal · 2023
This page describes a documented finding about the underlying wellness technology. It is not a marketing claim about any specific device. For information about HOCATT specifically, visit hocatt.com.