transdermal ozone activates key signaling pathways that trigger immune response and tissue remodeling
H₂O₂ generated by ozone activates NF-κB and TGF-β, increasing immunoactive cytokine release and upregulating tissue remodeling via phosphorylation of IκB through tyrosine kinase enhancement.
What this means for you
When your body's tissue-remodeling signals get turned up, it becomes better at responding to wear, stress, and damage at the cellular level. This kind of immune signaling activity is linked to how your body maintains and repairs connective tissue — something most people notice over time as improved resilience, recovery, and skin quality.
The published research
Ozone therapy: An overview of pharmacodynamics, current research, and clinical utility
Medical Gas Research · 2017
This page describes a documented finding about the underlying wellness technology. It is not a marketing claim about any specific device. For information about HOCATT specifically, visit hocatt.com.