transdermal ozone activates immune-signaling pathways in blood cells via hydrogen peroxide
Ozone therapy activates nuclear factor kB (NF-kB) in blood mononuclear cells via H₂O₂-mediated oxidation of selected cysteines, triggering synthesis of cytokines and acute-phase reactants that modulate the immune system.
What this means for you
Your immune system relies on precise chemical signals to stay responsive and balanced. When ozone contact triggers this cellular signaling cascade, it nudges the body's own immune-regulation machinery — the kind of low-level tuning that supports resilience, recovery, and a well-calibrated inflammatory response over time.
The published research
This page describes a documented finding about the underlying wellness technology. It is not a marketing claim about any specific device. For information about HOCATT specifically, visit hocatt.com.