ozonated saline supports immune modulation rather than direct microbial killing

Ozonated physiological saline at 1200 mcg/L did not produce direct bactericidal or fungicidal effects in vitro against Staphylococcus aureus, Escherichia coli, or Candida albicans, indicating its anti-inflammatory benefit is mediated through immune modulation rather than direct microbial killing.

What this means for you

This finding suggests that ozone's anti-inflammatory effects work by signaling your immune system — not by acting as a direct disinfectant in the body. That distinction matters: it points to a more nuanced, system-wide response that may support your body's own defenses rather than simply targeting microbes.

The published research

The Mechanism of the Anti-Inflammatory Effect of
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