transdermal ozone activates immune signaling pathways in blood cells via hydrogen peroxide

Ozone therapy activates blood mononuclear cells via hydrogen peroxide-mediated oxidation of cysteines, activating tyrosine kinase and nuclear factor kB (NF-kB), leading to synthesis of acute-phase reactants and numerous interleukins.

What this means for you

Your immune system relies on precise chemical signals to coordinate responses to stress, inflammation, and cellular damage. When key signaling pathways in blood cells are activated, the body ramps up production of proteins that support immune readiness and recovery — which most people notice as a greater sense of resilience and faster bounce-back after physical or environmental stress.

The published research

www.centauro.it Rivista Italiana di Ossigeno-Ozonoterapia 5: 93-104, 2006
· 2006
This page describes a documented finding about the underlying wellness technology. It is not a marketing claim about any specific device. For information about HOCATT specifically, visit hocatt.com.