transdermal ozone activates immune cells and triggers a natural cytokine response

Ozone therapy acts as a mild enhancer of the immune system by activating neutrophils and stimulating synthesis of cytokines via hydrogen peroxide-mediated NF-kB activation in blood mononuclear cells, representing a physiological cytokine response.

What this means for you

Cytokines are the signaling proteins your immune system uses to coordinate its response to stress, infection, and inflammation. When neutrophils — your body's frontline immune cells — get activated, your natural defenses become more responsive. This kind of mild immune stimulation is associated with better resilience and recovery.

The published research

Archives of Medical Research 37 (2006) 425–435
· 2006
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