ozone exposure reduces HLA-DR immune activation markers by more than half in blood cells
Ozone major autohemotherapy at 8 mg/session significantly decreased HLA-DR expression in peripheral blood mononuclear cells from 44% to 19% (p<0.05) in atopic asthma patients.
What this means for you
HLA-DR is a surface marker that signals how 'activated' certain immune cells are. When it drops significantly, it suggests the immune system may be shifting away from an overactive, inflammatory state — the kind linked to allergic responses, fatigue, and chronic low-grade inflammation. For wellness-focused individuals, a calmer immune baseline often supports better energy and recovery.
The published research
Changes in Glutathione Antioxidant Pathway Components,
This page describes a documented finding about the underlying wellness technology. It is not a marketing claim about any specific device. For information about HOCATT specifically, visit hocatt.com.