ozone exposure triggers fresh production of antioxidant enzymes, not just activation of existing ones

Ozone therapy induces de novo biosynthesis of antioxidant enzymes (SOD, CAT, GSH-Px) rather than merely activating pre-existing apoproteins, as demonstrated in E. coli cultures exposed to ozone.

What this means for you

Your body's antioxidant defenses aren't just a fixed reserve — they can be rebuilt from scratch. When ozone stimulates the creation of new protective enzymes like SOD and catalase, it may support a more sustained antioxidant response, which matters for managing oxidative stress tied to aging, inflammation, and slow recovery.

The published research

Mediators of Inflammation, 13(1), 13 /19 (February 2004)
· 2004
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