low-dose ozone shows cytotoxic effects on neoplastic cells and may increase sensitivity to 5-fluorouracil in lab studies
Low-dose ozone (< 0.5 ppm) for 24 hours was cytotoxic to neoplastic cells in vitro and potentiated the cytotoxicity of 5-fluorouracil, increasing sensitivity in a 5-FU-resistant colon carcinoma variant.
What this means for you
In controlled lab conditions, low concentrations of ozone appeared to act on cancer cells directly and made a drug-resistant cell line more responsive to a common chemotherapy agent. This is early-stage research — not a clinical outcome — but it points to ozone's potential role in supporting cellular stress responses worth following closely.
The published research
Ozone Therapy in Cancer Treatment. State of the Art
· 2020
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