ozone exposure reduces TNF-α by boosting antioxidant defenses and calming a key inflammation switch
Ozone oxidative preconditioning exerts its inhibitory effects on TNF-α production through stimulation of antioxidant defenses, which in turn inhibits NF-κB activation — a key transcription factor driving inflammatory cytokine expression.
What this means for you
TNF-α is one of the body's loudest inflammatory signals — when it runs high, you feel it as fatigue, soreness, and sluggishness. By nudging antioxidant defenses upward, ozone exposure appears to quiet the molecular switch that turns that signal on, which may support a calmer, lower-inflammation baseline over time.
The published research
Effects of Ozone Oxidative Preconditioning
· 2005
This page describes a documented finding about the underlying wellness technology. It is not a marketing claim about any specific device. For information about HOCATT specifically, visit hocatt.com.