transdermal ozone upregulates antioxidant enzymes and may reduce ischaemia-reperfusion injury

Ozone therapy may serve as a prophylactic treatment to improve organ transplantation success by upregulating antioxidant enzymes and minimizing ischaemia-reperfusion injury prior to transplantation.

What this means for you

When cells are starved of oxygen and then suddenly resupplied — a stress pattern that also occurs in intense exercise and poor circulation — oxidative damage spikes. Ozone exposure appears to prime the body's own antioxidant defenses in advance, which may support faster recovery and less cellular wear after periods of low blood flow.

The published research

Mediators of Inflammation, 8, 37–41 (1999)
· 1999
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