transdermal ozone reduces excess antioxidant enzyme activity toward normal range in diabetic tissue
Ozone treatment reduced glutathione peroxidase (GPx) activity in STZ-induced diabetic rats by 43% compared to untreated diabetic rats, while maintaining it above non-diabetic control levels, suggesting normalization of the antioxidant response.
What this means for you
When oxidative stress is high, the body overproduces certain protective enzymes trying to keep up. Ozone exposure appears to help bring that overactivation back toward a more balanced level — a sign the body's defenses may be working more efficiently rather than working overtime. That kind of balance is linked to better cellular resilience and recovery.
The published research
Ozone Therapy Effects in the Oxidative Stress Associated
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