ozone and far-infrared stimulate cGMP production, supporting blood vessel relaxation
Production of cyclic GMP (cGMP) - a second messenger
What this means for you
Mediates smooth muscle relaxation and vasodilation
The published research
Role of nitric oxide in orthodontic tooth movement (Review)
International Journal of Molecular Medicine · 2021
The review explicitly documents that NO activates soluble guanylate cyclase (sGC), which generates the second messenger cGMP from GTP within the cell, directly confirming cGMP production as a second messenger. The full text further details the NO/cGMP/PKG signaling pathway and its downstream effects in multiple cell types, establishing cGMP's role as a documented second messenger.
This page describes a documented finding about the underlying wellness technology. It is not a marketing claim about any specific device. For information about HOCATT specifically, visit hocatt.com.