heat stress during exercise raises creatinine and potassium, signaling greater kidney and electrolyte demand
Exercise under moderate heat stress significantly elevated serum creatinine (post: 1.03 ± 0.12 mg/dL vs. 0.9 ± 0.13 mg/dL under normal conditions) and blood potassium levels (post: 4.19 ± 0.22 mmol/L vs. 3.99 ± 0.17 mmol/L), indicating amplified renal and electrolyte stress.
What this means for you
When your body works harder under heat, your kidneys and electrolyte systems are pushed further than in normal conditions. Understanding this response is a reminder that hydration and mineral replenishment matter more in warm sessions — supporting recovery and helping your body bounce back efficiently.
The published research
Impact of moderate environmental heat stress during running exercise on circulating markers of gastrointestinal integrity in endurance athletes
Physiological Reports · 2025
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