heat stress activates brain cytokines and increases neural excitability in respiratory networks

Inflammation influences the development and function of neurons in brainstem respiratory networks and has widespread effects to elevate brain cytokines and increase brain excitability during heat stress.

What this means for you

When heat exposure nudges the brain's signaling environment, it can sharpen neural responsiveness — the kind of low-level activation that some people notice as heightened alertness or a clearer head after a session. This reflects how temperature-driven changes in brain chemistry influence the very networks that regulate breathing and arousal.

The published research

The Impact of Inflammation on Thermal Hyperpnea: Relevance for Heat Stress and Febrile Seizures
American Journal of Respiratory Cell and Molecular Biology · 2024
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