higher core body temperature correlates with increased markers of intestinal stress
Maximum core body temperature (Tc,max) was significantly correlated with post-exercise plasma levels of intestinal fatty-acid binding protein (I-FABP) (r = 0.554, p = 0.026), indicating that the degree of hyperthermia predicts intestinal epithelial injury.
What this means for you
When core temperature rises significantly, the gut lining can come under stress — a response researchers measure through proteins that leak into the bloodstream. Understanding this connection helps wellness-focused individuals appreciate why managing heat exposure duration and intensity matters for digestive comfort and overall recovery.
The published research
Impact of moderate environmental heat stress during running exercise on circulating markers of gastrointestinal integrity in endurance athletes
Physiological Reports · 2025
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