transdermal ozone significantly raises catalase activity and rebalances antioxidant enzyme ratios

Ozone therapy significantly increased catalase activity in diabetic foot patients (from 2112 ± 210 to 3101 ± 290 U/ml/min, P<0.05) and normalized the catalase/superoxide dismutase ratio (from 2.08 ± 0.10 to 0.51 ± 0.09, approaching healthy reference of 0.11 ± 0.20), while antibiotic therapy did not change catalase activity.

What this means for you

Catalase is one of your body's frontline defenses against oxidative stress — the cellular wear-and-tear linked to slow recovery, inflammation, and aging. When catalase activity rises and your antioxidant enzymes come back into balance, your body is better equipped to neutralize harmful free radicals and support tissue resilience from the inside out.

The published research

European Journal of Pharmacology 523 (2005) 151 – 161
· 2005
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